Life Extension
TMG
TMG
Life Extension's TMG contains trimethylglycine, also known as betaine.
- Trimethylglycine (betaine) in capsule form
- Dietary supplement
- See the label for the full composition and dosage
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Why we selected this product
Why we selected this product
We selected TMG (trimethylglycine/betaine) because it is one of the most commonly used ‘support tools’ within methylation and homocysteine routines. You can view methylation as a kind of ‘on/off switch’ in your body: it helps processes related to energy, hormones, and recovery run smoothly.
Homocysteine is a substance that can be measured via a blood test. If it is high, it can be a signal for some people to look into B vitamins and methylation support. TMG provides so-called ‘methyl groups’ (think: building blocks) that your body uses in these conversions.
Why Life Extension in particular: the brand is well-known in the longevity/biohacking world and places a strong emphasis on quality and transparency. We see TMG as a precision supplement: especially interesting if you work with biomarkers or want to make your routine truly targeted. It works best when used consistently.
With the BeatsWell Edit, we take the research off your hands. You choose with confidence: every product is carefully selected for quality and transparency. Read here more about how we select.
Scientific background
- Betaine attenuates chronic alcohol-induced fatty liver by broadly regulating hepatic lipid metabolism
- Effect of betaine supplementation on power performance and fatigue – PMC
- Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study
- Article Betaine, ethanol, and the liver: A review
- Effects of betaine on body composition, performance, and homocysteine thiolactone – PMC
- Betaine in Inflammation: Mechanistic Aspects and Applications – PMC
Usage
Usage
Use TMG only according to the recommended dosage on the label or the personal advice of your (healthcare) professional.
Take the capsules with water during a meal, unless your doctor advises otherwise.
It is best to have your homocysteine and relevant B vitamin levels monitored if you use TMG for a longer period of time, so that you know how your body reacts.
Always follow the dosage advice and if in doubt, consult your doctor or therapist before adding this product to your protocol.
Safety
Safety
Do not use TMG without consultation if you have severe kidney or liver problems or if you are taking specific medications, unless your doctor explicitly agrees.
Stop use and consult a doctor if you experience any adverse reactions such as persistent gastrointestinal complaints or unusual tiredness.
Store the product in a dry, dark place at room temperature, out of reach of young children.
Dietary supplements are not a substitute for a varied, balanced diet and a healthy lifestyle. Always consult the label for up-to-date information on dosage, ingredients, and warnings.

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Why BeatsWell?
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01 . Selected by the BeatsWell Edit
Only products that pass our strict Expert Standard become part of the BeatsWell Edit.
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02. Transparent about ingredients & quality
No noise. No hype. Just quality and ingredients that work for you.
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03. Fast shipping & easy returns
Order with confidence. We ship quickly and returns are easy.
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04. Personal support
Questions about your choice or routine? Email us at support@beatswell.com . We're happy to help.