TMG

Life Extension's TMG provides trimethylglycine (betaine), a substance that plays a role in methylation processes in the body.

Methylation is a biochemical process involved in DNA repair, detox pathways, and the metabolism of homocysteine, among other things. TMG is often combined with B vitamins such as folate, B6, and B12 in protocols that focus on this.

This product is intended for people who, in consultation with a (healthcare) professional, are following a targeted methylation strategy and wish to use trimethylglycine.

Provides trimethylglycine (betaine), a methyl group donor in one-carbon metabolism.

Can be combined with B vitamins in plans targeting homocysteine ​​and methylation (in consultation with a (healthcare) professional).

Capsule form for easy dosing within your daily routine.

Often mentioned in longevity, performance and biohacking contexts in combination with blood value monitoring.

We selected TMG (trimethylglycine/betaine) because it is one of the most commonly used ‘support tools’ within methylation and homocysteine routines. You can view methylation as a kind of ‘on/off switch’ in your body: it helps processes related to energy, hormones, and recovery run smoothly.

Homocysteine is a substance that can be measured via a blood test. If it is high, it can be a signal for some people to look into B vitamins and methylation support. TMG provides so-called ‘methyl groups’ (think: building blocks) that your body uses in these conversions.

Why Life Extension in particular: the brand is well-known in the longevity/biohacking world and places a strong emphasis on quality and transparency. We see TMG as a precision supplement: especially interesting if you work with biomarkers or want to make your routine truly targeted. It works best when used consistently.

With the BeatsWell Edit, we take the research off your hands. You choose with confidence: every product is carefully selected for quality and transparency. Read here more about how we select.

Scientific background

• Betaine attenuates chronic alcohol-induced fatty liver by broadly regulating hepatic lipid metabolism
• Effect of betaine supplementation on power performance and fatigue – PMC
• Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study
• Article Betaine, ethanol, and the liver: A review
• Effects of betaine on body composition, performance, and homocysteine thiolactone – PMC
• Betaine in Inflammation: Mechanistic Aspects and Applications – PMC

Use TMG only according to the recommended dosage on the label or the personal advice of your (healthcare) professional.

Take the capsules with water during a meal, unless your doctor advises otherwise.

It is best to have your homocysteine ​​and relevant B vitamin levels monitored if you use TMG for a longer period of time, so that you know how your body reacts.

Always follow the dosage advice and if in doubt, consult your doctor or therapist before adding this product to your protocol.

Ingredients: trimethylglycine (betaine), capsule material and excipients (consult the label for the full and current composition).

Check the label if you have any specific intolerances or allergies to any excipients or capsule material.

Do not use TMG without consultation if you have severe kidney or liver problems or if you are taking specific medications, unless your doctor explicitly agrees.

Stop use and consult a doctor if you experience any adverse reactions such as persistent gastrointestinal complaints or unusual tiredness.

Store the product in a dry, dark place at room temperature, out of reach of young children.

Dietary supplements are not a substitute for a varied, balanced diet and a healthy lifestyle. Always consult the label for up-to-date information on dosage, ingredients, and warnings.